NARSAD Researchers

In the News

Depression and Bipolar Disease

Research Advances

 

NARSAD researchers every day are making headway in understanding the nature of depression and bipolar disorder, and how best to treat these conditions. Here are three recent studies performed by NARSAD-affiliated scientists dealing with the causes and care of these psychiatric disorders.

 

Nobelist Discovers Antidepressant

Protein in Mouse Brain

 

A brain protein that seems to be pivotal in lifting depression has been discovered by Paul Greengard, Ph.D., the 2002 Nobel prize winner in Physiology/Medicine and a NARSAD Scientific Council member.

 

Mice deficient in this protein, called p11, displayed depression – like behaviors, while those with sufficient amounts behave as if they have been treated with antidepressants, according to Dr. Greengard, of Rockefeller University, who led the research, which was published in the January 6th issue of Science.

 

Dr. Greengard won NARSAD’s Lieber Prize in 1996 and was a NARSAD 1992 and 2002 Distinguished Investigator. Co-author Karima Chergui, of the Karolinska Institute, was a NARSAD 2002 Young Investigator.

 

The Rockefeller neuroscientist and his colleagues found that p11 appears to help regulate signaling of the brain messenger chemical serotonin, a key target of antidepressants, which has been implicated in psychiatric illnesses such as depression and anxiety disorders.

 

“This newfound protein may provide a more specific target for new treatments for depression, anxiety disorders and other psychiatric conditions thought to involve malfunctions in the serotonin system,” said Elias Zerhouni, M.D., director of the National Institutes of Health, which funded the study.

 

Women with Major Depression at Risk of Relapse during Pregnancy

 

Contrary to common belief that hormonal changes in pregnancy provide protection against depression, women with major depression who discontinue antidepressant medication during pregnancy risk relapse, according to a study performed by NARSAD-affiliated researchers and published in the Febuary 1st issue of the Journal of the American Medical Association.

 

Lee S. Cohen, M.D., of Harvard Medical School, and colleagues conducted the study to determine relapse risk in pregnant women with major depression who discontinued or who attempted to discontinue anti-depressant medication close to conception compared with those who maintained treatment. Dr. Cohen was a NARSAD 1993 Young Investigator and a 1998 Independent Investigator. Co-author D. Jeffrey Newport. M.D., of Emory University, was a NARSAD 2003 Young Investigator.

 

The study involved 201 pregnant women who had a history of major depression prior to pregnancy, were at less than 16 weeks gestation, and were currently (less than 12 weeks prior to last menstrual period) receiving antidepressant medication. The researchers found 43 percent of women relapsed during pregnancy; half during the first trimester. Among women who continued medication during pregnancy, 26 percent relapse compared to 68 percent of those who discontinued medication.

 

Such studies, the researchers say, provide quantitative data about the relative risk of prenatal exposure to medication and the risk of relapse, allowing clinicians and patients make better treatment choices.

 

Heritability of Major Depression is Higher in Women Than Men

 

Genes seem to contribute more strongly to risk of depression in women than in men, and some genetic factors may be operating uniquely in one sex and not in the other, according to findings from a NARSAD-affiliated researcher.

 

In the January issue of the American Journal of Psychiatry, Kenneth S. Kendler, M.D., of Virginia Commonwealth University, and colleagues at the Karolinska Institute reported that heritability of depression is higher in women – approximately 42 percent – than in men, where it is approximately 29 percent. Dr. Kendler won NARSAD’s Lieber Prize in 1995, was a NARSAD 2000 Distinguished Investigator, and is a member of NARSAD’s Scientific Council.

 

Sex-effects are of two kinds – quantitative and qualitative. Quantitative effects examine whether heritability differs in males compared to females, and if the overall importance of genetic factors differs between the sexes; whereas qualitative effects examine whether the same genes play a role in males and females.

 

For example, genes may alter the risk for depression in woman’s response to cyclic sex hormones, particularly in the postpartum period. Such genes would impact a woman’s risk for major depression, but would not be active in men.

 

 

COMBO DRUG THERAPY WON’T IMPROVE SCHIZOPHERNIA CARE

 

            Combining two antipsychotic drugs, clozapine and risperdone, offers no benefit in treating people with severe schizophrenia compared to use of either drug alone, Canadian researchers report.

The findings cast doubt on the widespread practice of “polypharmacy” for schizophrenia, when two or more drugs are prescribed together.

            “This study does not offer any support for antipsychotic polypharmacy,” says study author Dr. William Honer, a professor of psychiatry at the University of British Columbia in Vancouver.

            “The study is a very well-written report of a very meticulously conducted clinical trial, so it carries a lot of weight,” adds Dr. Leslie Citrome, a professor of psychiatry at New York University School of Medicine in New York City.

            The findings appear in the Feb. 2 issue of The England Journal of Medicine.

            Schizophrenia is a chronic mental illness with symptoms that can include hallucinations, delusions and disordered thinking. The disease affects about 3.2 million Americans.

           

 

 

 

 

 

The treatment landscape for schizophrenia has been relatively static over the past 15 years, experts say. The antipsychotic medication clozapine represented a major advance when it was approved in the United States in 1990. Drugs released since then have not provided any significant improvement for symptoms, although some have different side effect profiles, meaning they may be better tolerated by some patients.

“There has been an improvement in allowing us to match individual patients to individual medicines, but we are still frustrated at the inability to really control the symptoms of all illness in a patient,” Honer says.

Even adequately treated with the available drugs, as few as 20 percent of patients see all of their symptoms resolved. And because so many people have such a poor response to single antipsychotic drugs, the practice has been to describe multiple antipsychotic drugs - - despite a lack of evidence that is any more effective than using one drug alone.

“Current evidence for using more than one antipsychotic is limited to mainly anecdotal reports,” Citrome says. “A lot of people do use more than one, and think it’s driven by our desperate need to get patients better. However, the evidence doesn’t really support this strategy.”

According to Honer, 25 percent to 50 percent of patients who are being prescribed one antipsychotic medication are also taking another one, and sometimes as many as five.

In the study, the researcher wanted to see if symptoms improved when the antipsychotic drug Risperdone was added to the drug regimens of patients who had only a partial response to clozapine.

Both drugs are widely used antipsynotics.

In all, 68 patients with schizophrenia and a poor response to clozapine were randomly assigned to receive clozapine and a placebo or clozapine plus Resperidone for eight weeks, followed by an additional, optional 18 weeks of clozapine plus resperidone.

At end of the study period, the researchers found no statistically significant difference in symptom relief between the two groups. In other words, adding resperidone conferred no extra benefits.

This indicates that antipsychotic polypharmacy is unlikely to produce a major effect,” Honer says. “It doesn’t say anything about other combinations (for example, an antipsychotic with an antidepressant).”

So where does this leave patients struggling with schizophrenia?

One possibility is to combine antipsychotics with drugs in another class, such as mood stabilizer or antidepressants. Since they have different mechanisms of action, they might have better synergy,” Citrome speculates.

There may also be other ways to make single medications more effective, such as optimizing the dose or making sure medication is being taken on schedule.

Beyond that, however, Honer says we’re left with “the unexplored area of can we really come up with drugs that have different mechanisms that might really benefit people in ways that the current group of antipsychotic do not?”’

 

 

 

 

 

 

 

 

 

 

 

 

New Schizophrenia Clue:

Researchers detect abnormalities in one key gene that might disrupt

thinking and normal brain function

By Jamie Talan, News Day Staff Writer

 

For the first time, scientists have confirmed in human brains what they had already suspected: A large gene that regulates many brain functions is abnormal in people with schizophrenia.

 

The finding, published yesterday in the Proceedings of the National Academy of Sciences, provides clues to how the gene, neuregulin-1, might disrupt brain development and function and put people at risk for all sorts of thinking problems.

 

“This is a very interesting study,” said Dr. Gerald Fischbach, dean of the faculty of medicine at Columbia University, who added that this finding may one-day lead to new ways to treat schizophrenia. Fischbach and his colleague identified the gene in the early 1990s, and they suspected it had something to do with the nervous system. It’s only been in the past three years that a team of scientists in Iceland, at risk deCode Genetics, has linked the gene to schizophrenia. Since then, more than a half dozen laboratories have confirmed the link.

 

Amanda J. Law, a visiting scientist at the National Institute of Mental Health, and her colleagues analyzed autopsy material from 48 people with schizophrenia and 80 samples from normal brains. They found that the brains from people with schizophrenia had 30 percent higher expression of neuregulin-1 (Type 1) in the hippocampus and in the prefrontal cortex, regions of the brain involved with thinking and cognitive function.

 

In addition, they identified alterations of a novel form of neuregulin-1 (Type 4) that is also associated with increased risk for disease.

 

Alterations in neuregulin-1 may change the biology of gene and lead to abnormal regulation of its expression and function in the schizophrenic brain, Law said.

 

“We are trying to understand the biological consequences,” Law said. Scientists say they now have to figure out a way to measure neuregulin in living patients and identify ways to predict who may become ill and why.

 

Dr. Kari Stefansson, president and chief operating officer of deCode, identified neuregulin-1 as a risk gene for schizophrenia. Stefannson has reasons to go after the disease. As a trained neurologist and neuropathologist, he has watched his older brother live with schizophrenia.

 

Schizophrenia, which targets a person’s thoughts and emotions, strikes 1 in every 100 people, usually in late adolescence or early adulthood. Typically those who suffer from the disorder, which occurs in men and women equally and among all ethnic groups, suffer from disorganized thinking, delusions and hallucinations.

 

Neuregulin is a big gene with many roles in the body. It stimulates the formation of synapses, the space where two cells meet to communicate. It regulates remodeling at the synapses. And it is involved in making myelin, the protective insulation around nerve cells.

 

Dr. Kenneth Kendler, of Virginia Commonwealth University in Richmond, has been hunting for schizophrenia genes for decades. “We are slowly getting there,” Kendler said. “This is a real advance in the field.”

 

 

States Screening for Postpartum Depression

April 26, 2006

New York (AP) - - The attention goes to celebrity sufferers, such as Brooke Shields, or to grim cases in which mothers kill their children. But beyond the headlines about postpartum depression, states are making strides in raising awareness of the disorder and screening more mothers for it.

 

The boldest move has come in New Jersey, where a first-of-its- kind law was signed this month requiring doctors to educate expectant mothers and their families about postpartum depression and to screen new moms for the widespread condition.

 

“What New Jersey has done is phenomenal - - it’s what we want to have in every state in the union,” said Cheryl Hill, president of the Washington-based Family Mental Health Institute.

 

Several other states have launched awareness campaigns, including TV and radio spots in New York. On May 12, advocates for more ambitious federal action will lobby on Capitol Hill, including Edrienne Carpenter of Texas, who was battling postpartum depression when she won the 2004 Mrs. United States beauty pageant.

 

“I learned the hard way that there is a need for more educational awareness, emotional and physical support, and medical resources to be at the fingertips of women,” Carpenter says. “In today’s news, we’ve heard of too many cases that have ended in tragedy.”

 

Among recent criminal cases in which postpartum depression was cited as a possible factor were the 2001 drowning of five children in Texas by Andrea Yates, another Texas case in which a mother severed her baby’s arms, and the drowning of three sons by a Norfolk, Va., mother. Hill, who suffered from depression after her now-grown children were born, said the publicity about such cases has mixed consequences.

 

“People are starting to understand the disease a little bit more –that’s been helpful,” she said. “But it hurts women who suffer from postpartum depression. They’re afraid of coming forward. They don’t want to be labeled as crazy.”

 

Doctors and researchers say most new mothers experience occasional sadness and anxiety, known as the “baby blues,” that does not require treatment. Roughly 10 percent to 15 percent of new mothers suffer postpartum depression, a more serious condition which can affect a woman’s well-being and which, experts say, should be treated through therapy, group support or medication.

 

Emily Ashby, of Marshall, Va., says depression swiftly engulfed her after her first child’s birth five years ago.

 

 

 

 

 

 

 

“I had a fantastic pregnancy and was excited to be a mom,” Ashby said in a telephone interview. “But almost as soon as she was born, I know something wasn’t right.

 

“All of a sudden, I couldn’t drag myself out of bed in the morning, she said. “It became this black hole I fell into.”

 

She told her husband, but he was unfamiliar with postpartum depression and insisted Ashby could shake off the malaise on her own. After six weeks, she told her doctor, and eventually started taking drugs which rapidly restored her sense of joy.

 

Though she praised her doctor, Ashby said physicians should be more proactive generally in informing and questioning new mothers and their husbands about depression.

 

New Jersey’s program stresses a proactive approach. Over the past nine months, the Health Department has trained more than 4,500 doctors, nurses, psychologists and social workers to provide screening, referrals and treatment for postpartum depression.

 

Celeste Andriod Wood, assistant commissioner for family health services, said the department isn’t mandating a particular screening method. Its recommendations include the Edinburgh Postnatal Depression Scale, which asks 10 simple questions about emotions.

 

New Jersey has roughly 115,000 births a year, and Wood estimated that 10 percent of the new mothers will require intervention after positive screening for postpartum depression. Even if that increases referrals by 50 percent, the state has sufficient resources to cope, she said.

 

Dr. Paul Stumpf, head of the New Jersey branch of the American College of Obstetricians and Gynecologists, said most of his colleagues already sought to identify patients with depression, but he praised the new legislation.

 

“It’s matter of increasing the visibility of the problem, keeping it on the front burner,” he said.

 

The measure succeeded party because of strong support last year from then-Gov. Richard Codey and his wife, who had postpartum depression.

 

Nationally, the disorder has been chronicled in memoirs by former sufferers, such as actress Brook Shields’ “Down Came the Rain.” The book prompted actor Tom Cruise to publicly criticize Shields for taking antidepressants.

 

New Jersey’s initiative, based on recommendations from health professionals, contends that medication, counseling and support groups all can be effective.

 

Dr. Ralph Wittenberg, medical director of the Family Mental Health Institute, said drugs and psychotherapy each work in about two-thirds of postpartum depression cases. Used together, the success rate can exceed 90 percent, he said.

 

 

 

 

 
Therapies Make Gains Against Eating Disorders

April 26, 2006

 

WEST PALM BEACH, Fla. (Cox News Service) –No medications are available that effectively treat patients suffering from anorexia nervosa, but a few behavioral therapies may help prevent a relapse and offer other limited benefits, according to a new review of currently available research on eating disorders released today by HHS’ Agency for Healthcare Research and Quality.

 

The review also found evidence that several medications and behavioral therapies can help patients suffering from bulimia nervosa and binge eating disorder.

 

Eating disorders are psychiatric illnesses with potentially life-threatening consequences. Anorexia nervosa is characterized by an obsession with weight, severely restrained eating, sometimes exercising excessively, and an inability to maintain a healthy body weight. In bulimia nervosa, excessive eating is followed by efforts to compensate by vomiting, misusing laxatives or diuretics, fasting, or exercising excessively. Those with binge eating disorder eat excessively but do not purge.

 

Cognitive behavioral therapy (CBT), a form of psychotherapy that encourages patients to develop thinking patterns that will counteract their unhealthy eating behavior, helped prevent relapse in adult anorexic patients once their weight had been restored to normal. There was not enough evidence to determine whether CBT works during the acute please of the illness.

 

The researchers concluded that family therapy does not appear to work with adults with longstanding anorexia nervosa. One particular kind of family therapy, which starts by encouraging parents to oversee a young person’s nutrition, appeared to help these patients gain weight and make psychological improvements.

 

 

Good Counsel: Local Advice
Juvenile Onset Bipolar Disorder

Mario Testani, M.D.

                                                            From the D&C, summer 2006

 

Is your child or teen being treated for mental problem that does not seem to be getting better? Possibly bipolar disorder is cause.

Formerly known as manic depression, bipolar disorder typically causes cycles or swings of mood from depression to mania. Mania includes extreme happiness, excitement, boundless energy, unrealistic optimism, belief in one’s extraordinary power and ability, racing thoughts and speech, and anger.

Bipolar disorder may not present in its classic form, however, especially in the young. Hyperactivity, inattention, impulsivity, defiance and academic difficulties may be seen instead.

 

 

 

 

 

 

 

Since those symptoms occur in a number of others conditions, ranging from extremes of normal to anxiety, behavioral problems and attention deficit hyperactivity disorder, diagnosis is challenging. This is particularly true in the case of ADHD, which can occur with bipolar disorder. Psychological testing results in the two conditions may be identical.

Overwhelming, bipolar disorder is overlooked or misdiagnosed.

Treatments appropriate for a different condition, such as presumed ADHD, may cause disastrous immediate problems or more subtle instability over time despite initial improvement.

Evaluation for bipolar disorder is called for when there are:

·         Problems occurring in cycles. Periods between episodes may show milder symptoms or normal behavior.

·         Drastic personality changes during outbursts, often with cruelty and absence of remorse.

·         Sleep disturbances.

·         Loss of sense of reality.

·         Recurring depression or mania, or mixtures of these mood states.

·         Psychiatric problems, especially mood disorder, in the family history.

 

There is much more to recognizing bipolar disorder and knowing when to screen for it. Learn more from:

·         Child and Adolescent Bipolar Foundation, www.bpkids.org

·         Juvenile Bipolar Research Foundation (866) 333-5273 or www.bpchildresearch.org

·         Depression and Bipolar Support Alliance, which has area chapters. (800) 826-3632 or www.dbsalliance.org.

 

Mario Testani, M.D., is a clinical associate professor of psychiatry at the University of Rochester, practices at Crestwood Children’s Center and has a private practice in Pittsford.

CATIE Phase II Released

April 6, 2006- NAMI E-News Alert

 

On April 1, 2006, the latest in a series of major research studies funded by the National Institute of Mental Health (NIMH) into the effectiveness of psychiatric medications was released.

 

Known as CATIE II (Clinical Antipsychotic Trials of Intervention Effectiveness), the studies are part of the “Big Four” clinical trials that include STAR*D (Sequenced Treatment Alternatives to Relieve Depression), STEP-BD (Systematic Treatment Enhancement Program) for bipolar, and TADS (Treatment for Adolescent Depression Study).

 

CATIE, STAR*D, STEP-BD, and TADS are important because unlike clinical trails conducted by private industry, their focus is longer and comparative in nature, involving “real world” conditions. They provide essentials building blocks for a public research treatment “infrastructure” that can lead to newer, better medications.

 

 

 

 

 

 

 

 

 

Results from the second phase of STAR*D were released on March 23, 2006, the week before this latest installment in the return on public investment. Ironically, release of the studies comes at a time when President Bush has proposed cutting NIMH’S budget by $9 million. NAMI is fighting to restore the funds.

 

Medications Are Not Interchangeable

 

CATIE Phase II builds on an earlier study released last year, CATIE Phase I, that did not find dramatic differences in medication adherence when individuals were assigned randomly to either one old or several new antipsychotic medications.

 

NAMI’s analysis of CATIE I was that it raised more questions than answers. Later, NIMH also issued a clarification out of concern that state Medicaid programs might misinterpret the CATIE I results and lead them to restrict formularies to cheaper, older drugs. “A one –size-fits-all policy for treating schizophrenia could be harmful, essentially turning the clock back 40 years when conventional antipsychotic were the only medications available for patients,” NIMH declared. (CATIE Phase III will address cost effectiveness issues. NAMI will provide information about Phase III as it is released.

 

CATIE Phase II provides addition about choices in the treatment of schizophrenia. Different individuals respond differently to different drugs. If one medication is not fully effective in treating schizophrenia, the study provides guidance to doctors about switching to or adding a second drug.

 

CATIE II seeks to answer a basic and common clinical question – what factors might inform decisions about further treatment when a person does not respond to an initial antipsychotic medication?

 

·         For chronically ill individuals whose symptoms did not improve on the first medication, clozapine produced substantial reductions in symptoms and considerable improvements in medication adherence.

 

·         For those individuals who stopped their medication in Phase I because they were experiencing psychotic symptoms, olanzapine, and resperidone produced better medication adherence and better symptom reduction than ziprasidone or quetiapine.

 

·         For People who stopped taking medication during Phase I because of side effects, no differences were noted between olanzapine, resperidone, ziprasidone, or quetiapine in reducing side effects.

 

These results once again demonstrate that antipsychotic medications are not interchangeable. What works for one person may not work for another.

 

 

 

 

 

 

 

 
“Being Heard in Rochester

Awareness Project

Invitation to Share Personal Examples of Stigmatizing Language

 

 

Have you overheard, encountered, or addressed stigmatizing language? Here is an opportunity to enhance awareness though sharing your experience.

 

One way to monitor and influence how the public perceives people who are living with biologically-based brain disorders is to explore what is being heard in day-to-day conversations.

 

Because communication is two-way, it is important to examine and record not only any language that is stigmatizing, but also the language that is chosen to address it, the intended audience becomes collective; we all choose language and engage in conversations in order to be heard, and we only know how or if we are being heard by what is said after we speak.

 

This project will have several phases. The first part will be collecting specific examples from those who respond to this solicitation. The second part will be putting those exchanges into a creative format that can be presented to an audience. The goals of this presentation are multiple: to raise awareness of language that is stigmatizing (and of language that is informed and compassionate); to gather a wide audience for exploring an issue that has been slow to evolve, namely, informed and compassionate perception and treatment of this issue as seen through our selection of language; and finally, to foster growth and community by inviting people to engage in a post-presentation Q and A, so that understanding and communication can be improved. By providing real conversational snippets that reflect what is being heard in Rochester, we will be taking a pulse from which we can take real steps forward, together.

 

 

Project Focus:

Those experiencing stigma from biologically-based brain disorders such as severe depression, bipolar, or schizophrenia. This project will include examples from range of perspectives—from advocate, family and friend, those living with these illness, and provider.

 

Who Should Respond:

Those who can relate some specific actual language or conversations: what they heard, how they addressed it (or why they didn’t), how the person responded, and any final outcome.

 

 

 

 

 

 

 

 

 

 

 

 

What to Include:

1.      Your name, gender, age, telephone number, mailing address, and email address, if desired.

2.      Whether you experiencing stigma-causing language as an advocate, family member (please specify relationship), friend, person living with one of the illnesses, or as provider.

3.      If you are living with an illness, please state which one, how many years you have been living with it, and how long it has been diagnosed.

4.      A few sentence (no more than one paragraph, please), that tell what stigma-causing language you heard, how you responded (or why you didn’t), and what transpired afterwards. (This is an initial way to ensure the project has representation from different perspectives. Actual interviews will cover the details of each encounter with stigmacausing.)

 

How to Submit:

 

*Drop off your contact information in a envelope marked “Being Heard in Rochester at the NAMI office during office hours (Mon-Thurs, 9:00 AM– 4:00 PM), or during the NAMI monthly meeting (held the fourth Monday of each month, 6:30-9:00 PM)

*Mail your contact information to:

Terri Ann Bourke, P.O. Box 10665, Rochester, NY 14610

*Email your contact information to:

BeingHeardInRochester@frontiernet.org

 

What This Project Isn’t Focused Upon:

The project is not collecting examples of stigma-causing language from the media. (Movies, cartoons, television, or newspaper and magazine articles) Nor is it a solicitation for general stories related to these illnesses. (History or what it is like to experience them) If, however, a stigmatizing comment is heard in response to a media form, or in response to a discussion about someone’s illness, it will be consistent with this project’s focus.

 

Important: Confidentiality will be protected in a number of ways: no real names will be used in the project, and actual examples/stories will be represented in a way so that actual identities would be difficult to identify or confirm. (Perhaps some details will be omitted, or expressed in general terms.) Notes and tapes of interviews will be kept confidential, and in possession of the project head.

 

Process: After a good number and representation of submissions have been received, people will be contacted to arrange for one-hour interview sessions. Some people will be contacted to meet for a one-on-one interview, and others will be invited to be part of a small-table discussion. A timeline and end date will be communicated, as they become more apparent.

 

Here’s to fostering positive change,

 

Terri Ann Bourke, NAMI Member

 

 

 

 

 

 

 

Recovery from Serious Mental Illnesses

 

 

What is Recovery?

 

Many people using the health care system are in the process of recovery; for some it’s healing from surgery to walk without pain and return to work; for some it’s getting past effects of chronic asthma and being able to join in activities again; for some it’s beating cancer and watching a son or daughter graduate from high school.

For roughly 8 million Americans who live with a serious mental illness* and their families, recovery means living life to its fullest, having relationships, being part of a community, holding down a job, going to school. Recovery means living a satisfying, hopeful and contributing life, with or without the limitations of a psychiatric disability.

 

Is recovery possible?

 

While the way in which recovery happens may be different for each person depending on the nature of the issues he or she is struggling with, research on advances in mental health demonstrates that recovery from serious mental illness (for example, schizophrenia, bipolar disorders and others) is a real possibility.

 

In the past, people with serious mental illnesses often were told they would probably get worse over time and lose much of what was important to them, such as their jobs and friends. Contrary to this myth, people with psychiatric disabilities can recover. For example, data from around the world show that more than 5% of those struggling with schizophrenia over several decades, significantly improve or even recover.

People living with a serious mental illness work as managers, professionals or anything they have an interest and talent for, they go back to high school, college or other types of education.

 

What is recovery like for someone living with a serious psychiatric disability?

 

Recovery from a mental illness involves more than recovery from the mental illness it self. People with mental illness may have to recover from the discrimination they have incorporated into their very being, from lack of recent opportunities for self-determination, from the negative side effects of unemployment, and from crushed dreams.

The recovery journey often happens in phases. At first, the person may be in shock, denying that anything has changed or happened. The person may go through grief, despair and depression, as the meaning of his or her situation sinks in. Over time this often gives way to periods of anger and acceptance. Finally hope, coping and a sense of empowerment develop as the individual’s recovery strengthens.

Recovery for people living with a serious mental illness is a journey that involves a network of supports. These supports may include self-help groups, families, and friends. They may also include the use of medications and supportive therapy along with rehabilitation to develop needed skills and supports.

 

 

 

 

 

 

 

 

Resources

 

Part of recovery includes increasing knowledge and control. Here are some organizations that can provide more facts about the topics discussed and/or connections to local resources.

 

·         Center for Psychiatric Rehabilitation, www.be.edu/cpr

·         NAMI National Alliance for the Mentally Ill, 1-800-950-NAMI (6264)

www.nami.org

·         National Empowerment Center, 1-800-POWER-21 or 1-800-769-3728

www.power2d.org

·         The Mental Health Consumer Self Help Clearing House, 1-800-553-4553, www.nmha.org

 

 

Antidepressants Approval for Winter Blues

June 12, 2006

 

WASHINGTON – An antidepressant won federal approval Monday as the first drug to treat seasonal affective disorder, the wintertime blues that can strike when the days grow short.

 

Wellbutrin XL can be used in the prevention of major depressive episodes in patients with a history of seasonal affective disorder, often called SAD, the Food and Drug Administration said. SAD is characterized by recurrent major depressive episodes during the fall and winter.

 

The FDA approved Wellbutrin XL – the extended release version of bupropion HCL in tablet form – in 2003. The original version of the drug won approval in 1985.

 

Food and Drug Administration: http://www.fda.gov/

 

Upcoming Events at the Mental Health Coalition :

                        (WRAP)          Wellness Recovery Action Plan

                                                By Rita Cronise, M.S.

                        Date:                August 25, 2006                     

                        Time:               2:00-4:30 p.m.

                        Location:         Mental Health Coalition

                                                339 East Ave. Suite. 201

                                                Roch, NY 14604

                        RSVP               to Sam at 325-3145 x 42

 

A WRAP is a structured way to regain and maintain a healthy lifestyle by identifying and    

Creating a plan to deal with symptoms or stresses before they reach a critical state. This will be a brief overview of the key concepts of recovery and the parts of a Wellness Recovery Plan. After attending the workshop, you will be able to create a WRAP on your own or you can plan to attend a series of structured workshops that will be available through the Mental Health Coalition beginning September 8th.

 

A weekly Depression and Bipolar Support Alliance ( DBSA) group is also planned to start on Fridays in September at the Mental Health Coalition. Call Rita Cronise at 924-7936 for more information.

 

 

 

 

Bipolar Disorder Research Study ( New)

            Do you know a woman, age 14-17 years, 28-39 years, or 50-70 years, who has been diagnosed with Bipolar Disorder? If so, she may be eligible for a 2-visit study about stress and physical health being conducted at Strong Memorial Hospital/ University of Rochester. Payment for participation in this study is $20 upon completion of the second visit. For more information, please call Namrita at (585) 273-4488 or email: namrita_malhi@urmc.rochester.edu.

 

Purpose of Study:

            The purpose of this study is to try to determine if increased levels of IL-6 , a blood protein that can cause inflammation, and cortisol, a hormone made by the adrenal glands, occur in response to a psychological stressor in bipolar women at three different time points in the lifespan. The study will also examine if elevations in IL-6 and cortisol are related to risk factors you/your child may have for heart disease, diabetes, and osteroporosis. These results will give us information for future studies to examine whether IL-6 and cortisol are related to other medical illnesses, including cardiovascular disease, osteoporosis, and obesity, in the bipolar population.

 

 

 

 

WELCOME THESE NEW MEMBERS

 

TO THE NAMI FAMILY!!!!!!

 

Donna Long                            Georgette Lesnak                    John & Judy Messenger

 

Ann Marie Giannosa               Sue Zartman                            Teresa Madau

 

Charles Dick                           Daune Parsons                                    Judy Weiner

 

Janet Thompson                      Sandra Nettles Lechebo          Patty Chapman

 

Barbara Spector                      Jan Karman                             Lou Ann Haesser

 

Christine Liu                           Margaret McIrvine                  Valerie Levine

 

Karina Churchill                      Tammy Englert                       Cindy Groves

 

Peggy Hobbs                           Beth Hoh                                Jeanette Plymale

 

Raul Perez                              

 

New Board Members Elected:

Four new board members were announced at the Annual Dinner on April 24th:

George Campbell        Jodie Terhune              Mary Robbins             Aaron Taub

George and Jodie are first time members, Mary and Aaron are returning members who each previously served on the board for six years. We welcome all !!

 

New Officers elected at the May board meeting:

President                     Judy Watt, MS.RN.

1st Vice President        Larry Guttmacher, M.D.

2nd Vice President       Nancy Carlucci

Treasurer                     Don Anderson

Secretary                     Sherlaine Shelley

 

Amendment # 8 to the By Laws ( Article VIII – Officers)

This amendment was approved by more than two-thirds of the members present at the monthly meeting on June 26, 2006. It states that the officers of the corporation shall be the President, First Vice President, Second Vice President, Treasurer and Secretary. Previously, there was just one vice president. The reasons for adding the 2nd vice president position are that the organization is growing and the board wanted a stronger, larger executive committee and  it will model what is being done in the larger New York state affiliates as well as the NAMI/NYS board of directors.

 

Donation from Molly Lee Campbell Foundation

NAMI thanks George Campbell for the unrestricted donation of $2500 from the Molly Lee Campbell Foundation to be used to benefit the supports and services that NAMI provides for individuals and families affected by mental illness.

 

 

 

 

 

 

Our Deepest Sympathy to the Family of “Billy” Ripperger

NAMI Rochester expresses our deepest condolences to Cathy and Bill Ripperger, longtime members of NAMI Rochester who lost their son, Billy, to mental illness on June 16, 2006. Cathy has volunteered for several years as hostess at our monthly meetings. She said that she and Bill will always be grateful to NAMI for the support and friendship that they received as members of NAMI and they will continue to support NAMI Rochester.

 

Intern from the Rochester Urban Fellows Program

This summer NAMI is pleased to have Maggie Lindstrom, who will be a 4th year student at the U of R this fall, working in the NAMI office to complete requirements for her program. She has been working with Rita Cronise, board member to conduct surveys and gather data from our members for the purpose of completing the NAMI board of directors strategic planning for the future. Many of you have met and or talked to Maggie over the phone and we thank you for your responses to our survey. Maggie is also working with the Young Adult group, under the direction of Judy Watt. ( See article below).In addition to all this, she has spent a lot of time in the NAMI office, helping Sherlaine and Pat with numerous tasks. We will all miss her smiling face and energetic personality and we wish her the best with her continued studies at the U of R this fall. Maggie plans to stay active with the NAMI group as she continues with the Young Adult Group and the plans to develop “NAMI On Campus.”

 

NAMI Young Adult Group

The NAMI Young Adult group will be meeting every month during the regular education/support meetings on the fourth Monday.  This group is for consumers and family members who are 18+ and are interested in gaining support and education that is relevant for young adults. In addition to the regular meetings, the group will be planning social events and some members will be exploring the idea of starting NAMI on campus affiliates at area college campuses. Come check us out August 28 at 6:30 p.m., at the Reformation Lutheran Church during the regular meeting.  If you have any questions, call the NAMI Rochester office at (585) 423-1593.

 

Congratulations to Special Award Recipients:

Special awards were presented at the Annual Dinner on April 24th. NAMI volunteer recognition awards were given to Nancy Brackmann, Claire Perlman and Rich Sine for all the time and dedication that they have given to NAMI in the past year.

Thomas Jewell, Ph.D. from the Family Institute was presented with the Community Service Award for his work with the Family Institute and NYS Office of Mental Health in collaboration with NAMI/NYS.

Eric Weaver, retired director of the Rochester Police Department’s EDPRT ( Emotionally Disturbed Persons Response Team) was presented with the First Annual Karen Cavalieri Consumer Empowerment Award for his outstanding job as coordinator  and trainer for this special police team.

 

Jack Goldstein Receives 2006 Distinguished Volunteer Award from the Mental Health Association.

Jack, who is a board member and facilitator for NAMI Rochester and a board member for the Mental Health Coalition, was honored at the Mental Health Association’s Annual Award Event. When the director of the coalition left her position after many years and the size of the board had substantially decreased, Jack voluntarily took responsibility for identifying a number of peers in the community who were committed to the mission of the Mental Health Coalition and wanted to see it continue and prosper. Jack took over the role of co-chair person of the Board, giving up many hours of this personal time to review resumes and interview candidates. Pat Woods, executive director of the Mental Health Association, who presented the award, spoke about how Jack became a sounding board as to what peers were looking for in a director and later took a leadership role in the hiring of a new Director.

 

 

LEGISLATIVE NEWS from NAMI/NYS

We in NAMI-NYS are grateful to the New York State Legislature for:

 

    1. Approving bill S.2207C,  limiting the placement of state prisoners with serious mental illness in "Special Housing Units," and providing them with an alternative to solitary confinement.  "The SHU Bill" passed the Senate by a vote of 61-0. 

     2. Approving bill S.03653, which, among other things, requires the establishment of community housing waiting lists within the office of mental health service system and directs each provider of housing services in the office of mental health system to provide, on a monthly basis, the office of mental health with a list of each person referred to, admitted to, applying for, withdrawing an application for and denied admission to housing provided by such provider

An impassioned speech by Senate Mental Health Committee Chairman Thomas Morahan paved the way for its approval. If this bill becomes law, there will finally be an accurate assessment of the acutal need for community mental health housing in New York State.

     3. Coming to an agreement between both houses and with Timothy's Law Campaign on a Timothy's Law health insurance parity bill. (Unfortunately, time ran out and the session was adjourned before the bill could be voted on). We got less than what we asked for, but far more than what was offered last year. It was the judgment of Timothy's Law Campaign that it was an offer we couldn't refuse. Please see the press release below for a descripton.

     4. Overriding the Governor's vetoes to the state budget to insure the following:

    Extension of Medicare Part D Wraparound: The Legislature and the Governor agreed to extend Medicaid Wraparound Drug Coverage for Dual Eligibles who have difficulty obtaining necessary medications from their Medicare Part D Drug Plan until January 1, 2007.  This coverage had originally been set to expire at the end of this month. 

    Restoration of Physician Override: This ensures that a physician has a final say in what medications are prescribed for his or her patients under the Medicaid Preferred Drug Program. The original Executive Budget sought to remove the patient protection.

    Efficacy, not cost, will be the determining factor in what medications are selected for the Medicaid Preferr